Mitochondrial DNA (mtDNA) is DNA found in the energy-producing cell structures known as the mitochondria. Unlike nuclear DNA, which is inherited from both parents, mtDNA is inherited only from the mother.
mtDNA can be used in cases where other forms of DNA analysis may not be possible due to degradation or low quantity of DNA. Because mtDNA is present in multiple copies per cell, it can often be extracted from old, degraded, or size limited samples such as hair, bones, and teeth. Mitochondrial DNA analysis can identify missing persons, determine family relationships, and to link individuals to geographic regions or ethnic groups. Though mtDNA cannot identify an individual, as being maternally inherited it is shared among relatives, it is useful in providing additional DNA evidence in critical investigations.
mtDNA Testing Through Massively Parallel Sequencing
Bode technology continues to innovate and invest in technology, instrumentation, & other sequencing solutions. By combining instrumentation such as the S5 Platform, MiSqeq, and Ion Chef Systems, we can rapidly and accurately create template libraries and enable the preservation of collected evidence.
Complex mixture resolution
Alternative DNA processing for challenging samples
Predictive genomics including phenotypic traits and biogeographical ancestry.
Geosourcing and Ecomapping
Forensic microbiome exploitation
Alternative forensics DNA markers including SNPs and microhaplotype
PSA or p30
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Massively parallel sequencing optimizes degraded DNA.
Bode’s expert forensic capabilities and instrumentation enable accurate and reliable testing and analysis of the most challenging DNA samples.